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  LiveWire / Teen Forums / Science & Business / Viewing Topic

When people snort drugs, how do they get to the brain?
Replies: 74Last Post Aug. 28, 2008 8:07pm by TheOtherHorseman
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my guess: First they go to the lungs

then they get absorbed in the lungs in go in the bloodstream with the oxygen

and then they go up to the brain...

but then once up to the brain how do they work

does the brain have to soak them up or something

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Nope.

Mucus Membrane. They get absorbed on the blood rich mucus membrane.

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Alters Brain Chemistry and ways you process things and such.

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House would know

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Quote: from drifting at 5:53 pm on Aug. 28, 2008

Nope.

Mucus Membrane. They get absorbed on the blood rich mucus membrane.


o i c.

Ok then what

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Quote: from drifting at 1:53 am on Aug. 29, 2008

Nope.

Mucus Membrane. They get absorbed on the blood rich mucus membrane.


Assuming the drug can pass through the blood-brain barrier, otherwise it's useless what you snort.

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Absorbed through the mucos membrane, which then allows them to enter the mucus membrane.

In order to get to the brain they have to ahve the right chemical properties to cross the blood brain barrier

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Ok tell me how this works, does the brain just soak your powder up like a sponge and go, "this texture makes me want to increase my dopamine!"

I think not.

I need to know, they don't even have this information on the Internet.

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Quote: from Its Bearsy Bitch at 8:55 pm on Aug. 28, 2008

Quote: from drifting at 5:53 pm on Aug. 28, 2008

Nope.  

 Mucus Membrane. They get absorbed on the blood rich mucus membrane.


o i c.  

Ok then what


I assume the chemicals then inhibit, or stimulate senders/receptors in the brain, causing the brain to misfire, throwing you into an alter state of consciousness.

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Quote: from greatescape11 at 5:55 pm on Aug. 28, 2008

Absorbed through the mucos membrane, which then allows them to enter the mucus membrane.

In order to get to the brain they have to ahve the right chemical properties to cross the blood brain barrier


so do they not really go in your brain

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Quote: from drifting at 5:57 pm on Aug. 28, 2008

Quote: from Its Bearsy Bitch at 8:55 pm on Aug. 28, 2008

Quote: from drifting at 5:53 pm on Aug. 28, 2008

Nope.

  Mucus Membrane. They get absorbed on the blood rich mucus membrane.


o i c.

 Ok then what


I assume the chemicals then inhibit, or stimulate senders/receptors in the brain, causing the brain to misfire, throwing you into an alter state of consciousness.


Oh right... so the chemicals in the powdered drugs would combine with the chemicals in the cns and they would fizz and the cns would think it's supposed to fire extra shots of feel good neurotransmitters

amirite

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Quote: from Its Bearsy Bitch at 9:01 pm on Aug. 28, 2008

Quote: from drifting at 5:57 pm on Aug. 28, 2008

Quote: from Its Bearsy Bitch at 8:55 pm on Aug. 28, 2008

Quote: from drifting at 5:53 pm on Aug. 28, 2008

Nope.    

   Mucus Membrane. They get absorbed on the blood rich mucus membrane.


o i c.    

  Ok then what


 

 I assume the chemicals then inhibit, or stimulate senders/receptors in the brain, causing the brain to misfire, throwing you into an alter state of consciousness.


Oh right... so the chemicals in the powdered drugs would combine with the chemicals in the cns and they would fizz and the cns would think it's supposed to fire extra shots of feel good neurotransmitters

amirite


Thats how I understand it.

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Quote: from Its Bearsy Bitch at 2:01 am on Aug. 29, 2008

Oh right... so the chemicals in the powdered drugs would combine with the chemicals in the cns and they would fizz and the cns would think it's supposed to fire extra shots of feel good neurotransmitters

amirite


No, not really.
It depends from drug to drug, but usually either the drug inhibits the breakdown of neurotransmitter causing large amounts to remain inside the synaptic cleft (such as with MDMA I believe), or the drug can prevent the neurotransmitter from forming causing less action potentials to be transferred and hence less propagation of the impulse. Or it can be something else too. There're lots of ways drugs can have effects on the brain.

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Quote: from Its Bearsy Bitch at 7:58 pm on Aug. 28, 2008

Quote: from greatescape11 at 5:55 pm on Aug. 28, 2008

Absorbed through the mucos membrane, which then allows them to enter the mucus membrane.  

 In order to get to the brain they have to ahve the right chemical properties to cross the blood brain barrier


so do they not really go in your brain

Yes they do.....how was that hard to understand at all?

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Quote: from marshmellowman at 6:04 pm on Aug. 28, 2008

Quote: from Its Bearsy Bitch at 2:01 am on Aug. 29, 2008

Oh right... so the chemicals in the powdered drugs would combine with the chemicals in the cns and they would fizz and the cns would think it's supposed to fire extra shots of feel good neurotransmitters  

 amirite


No, not really.
It depends from drug to drug, but usually either the drug inhibits the breakdown of neurotransmitter causing large amounts to remain inside the synaptic cleft (such as with MDMA I believe), or the drug can prevent the neurotransmitter from forming causing less action potentials to be transferred and hence less propagation of the impulse. Or it can be something else too. There're lots of ways drugs can have effects on the brain.

I know but I'm saying for example, I was just asking how it gets up there in the first place and tricks the brain into doing stuff

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