When I first read this, the first thought that came into my head was "Why did this start?!" Did one day you just not go out and then stop it all together over time? Did something happen that you felt the need to just hide away in your bedroom? I understand what you mean by just going out and meeting new people would be difficult. Of course it is. Making friends is a hard thing to do and makes some people very uncomfortable. You need to do what makes you comfortable. Take one day at a time. Start by hanging out with your friends again. Stop yourself from sitting in your bedroom everyday. Make an effort to meet up with them and hang out again. You are in college, right? (you zone is set to College) You shouldn't be just sitting alone and hiding. You should be out and about, having a good time with friends and just enjoying life. At the moment, you are just wasting your life by not doing anything. Get out of this depression by having a good time with your friends and over time, you'll be able to go back to cracking jokes with friends, meeting new people again and overall be back to your old self.
As for your friends not caring about you, do you realise how silly that sounds? Of course they will! For all those casual acquaintances that you said "hi" to, did you ever think they would be wondering where you are and why you stopped saying "hi"? Sure, probably the next time you do stop and catch up, they could even start asking where you have been. The point is, you disappearing hasn't gone unnoticed. I bet your friends miss you hanging out with them and telling them jokes!
At the end of the day, this is up to you. You need to stop staying at home in your room alone and start making an effort to be your out self again. Will it take time? Yes. Will it be easy? Probably not. But can you do? Of course you can! You just have to put your mind to it and you can achieve anything.
I really hope that helped! You can message me if you would like to talk. Good luck.