any suggestions, also i have microsoft anti-spyware, is it worth keeping?
I suggest you try KasperSky. I recommend this as the #1 choice.
http://www.download.com/Kaspersky-Anti-Virus-Personal-Pro/3640-2239-10333027.html
Try deactivating system restore and starting up in safe mode and do a full virus scan.
you cant run a scan in safe mode, the antivirus will be dissabled