Quoting Post Archived Topic: It will not be bumped to the top of the forum. Topic Difference between hydrochloride and hydrobromide? Membername   Not a member? Sign Up Free (takes 20 seconds) Password   Forgotten your password? Post Font: Verdana Arial Black Georgia Comic Sans Impact   Size: Tiny Normal Big Huge   Color: Default Dark Red Red Orange Brown Green Olive Cyan Blue Dark Blue Indigo Black [ Check Spelling ] [ Post Preview ] [ LiveTags ] Quote: from [mod]marshmellowman[/mod] at 7:13 am on Jan. 9, 2009[quote]Not much difference really. Chemicals like that are often given as salts, because this is often the easiest way to make them into powder/tablet form. Whether or not it's a bromide or a chloride or sulphide shouldn't really matter much, because that's not the part of the chemical that is pharmacologically active, the rest of it is (ie the citalopram). Just like IV injections of morphine are often found as morphine sulphate, chemicals that need to be stabilised or converted into another form for distribution can have a salt group or other group added onto it. So the side effects and the price shouldn't be affected by it. That said, sometimes the process to make a specific iteration might be cheaper, but that doesn't mean the effects of it are any less or the more expensive version is any better.[/quote] FAQ Keyword Search: Post Options Favorites Manager Notify me of new replies to this topic by email Notify me of new replies to this topic by private message Original Post Daleacus Posted at 7:10 am on Jan. 9, 2009 Say someone was taking citalopram hydrochloride and were suddenly given their next set of tablets as citalopram hydrobromide. What's the difference? Why the sudden change in the second name - one likely to be cheaper than the other or something? Reckon any side effects migth alter?

Replies Daleacus Posted at 7:42 am on Jan. 9, 2009 Ah, ok. Thanks people. =P Was curious. It was either ask here or bore my chemist with uneducated questions. osmoticdespair Posted at 7:17 am on Jan. 9, 2009 The HCl/HBr is not the active part. It just makes it a salt as marshmellowman says. The only real difference will be in weight. Kitty Kiska Posted at 7:14 am on Jan. 9, 2009 I think choloride and bromide are within the same family of chemicals arent they...so there for minor changes since the rest of the chemicals used seem to be the same. marshmellowman Posted at 7:13 am on Jan. 9, 2009 Not much difference really. Chemicals like that are often given as salts, because this is often the easiest way to make them into powder/tablet form. Whether or not it's a bromide or a chloride or sulphide shouldn't really matter much, because that's not the part of the chemical that is pharmacologically active, the rest of it is (ie the citalopram). Just like IV injections of morphine are often found as morphine sulphate, chemicals that need to be stabilised or converted into another form for distribution can have a salt group or other group added onto it. So the side effects and the price shouldn't be affected by it. That said, sometimes the process to make a specific iteration might be cheaper, but that doesn't mean the effects of it are any less or the more expensive version is any better. The Fantasy Posted at 7:11 am on Jan. 9, 2009 Nah the side effects wouldnt be any different. All 5 previous replies displayed.