-- Posted by ohemgeeitsme at 2:57 pm on Nov. 25, 2008 I have a bottle of generic lortab (hydrocodone/acetaminophen) syrup from 2005... looks the same as it did then, do you think its gone bad? -- Posted by Vicodin at 2:59 pm on Nov. 25, 2008 Nope. Isn't that that yellow drank shit? I've taken my codeine/prometh syrup when it was like 3 years old. -- Posted by anc8469 at 3:00 pm on Nov. 25, 2008 eh medication usually expires within a year. Idk if it has gone bad, but it might not be as full in effect as it use to be. I wouldn't take it just to be on the safe side. -- Posted by Xusk at 3:44 pm on Nov. 25, 2008 Drugs tend to not turn into poisonous substances over time(like some people want you to think), they just degrade overtime especially when there not stored properly. I'd be careful abusing the stuff if there's Acetaminophen though, that stuff is worse then Alcohol on your liver.