-- Posted by grinzbie at 3:43 pm on June 17, 2008 I have been taking it for almost 2 weeks and it really helps with my mood-swings and anxiety but if i miss jsut one day and I dont take it I get really overwhelmed...But I was just wondering if anyone else is in the same situation or know of any side-effects..; Thanks -- Posted by bluerosedangel at 3:49 pm on June 17, 2008 My neurologist prescribed it to me back in 2005 for depression. It made me more suicidal, gave me more headaches, more anxiety, and kept me awake. I stopped taking it needless to say, because I cant swallow pills so I had to chew the zoloft, on top of my epilepsy medication. But that's just how it affected me. Medication affects each individual differently. -- Posted by lostwitness at 3:50 pm on June 17, 2008 Celexa & Lexapro are the most effective SSRI's. Period. -- Posted by IamMelissa at 3:52 pm on June 17, 2008 I was on zoloft once. I hated it. it made me feel worse. Then I started on Lexapro. It did very well. I was weaned off of it and I am better. -- Posted by ilyjosh at 8:18 pm on June 17, 2008 I was on Zoloft for a couple of months last summer. It didn't help. It made me very emotional.